research AI for maternal-fetal disease prognosis Models that read the state of stromal cells at the maternal-fetal interface to predict pre-eclampsia and fetal growth disorders. Evolved stromal resistance to invasion Why stroma resists invasion by placental and cancer cells in some mammals, and which genes and regulators explain it. Oscillatory hypoxia in cancer How oxygen that rises and falls, rather than staying low, rewires gene expression in cancer cells and surrounding stromal cells. Cell-cell communication and secretomes Models and data analysis of how cells exchange molecules, from tunneling nanotubes and secretomes to tissue-wide signaling maps. methods Network and statistical methods Graph, epidemic and machine learning methods that cope with noisy, incomplete and biased biological and clinical data. Signal processing for neural interfaces Wavelet compression, spike detection and neuron clustering for implantable recording devices, plus a hearing-aid noise suppression idea.
